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ADWX 1
CAS No. ——
ADWX 1 ( —— )
产品货号. M30750 CAS No. ——
Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a model for multiple sclerosis.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称ADWX 1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a model for multiple sclerosis.
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产品描述Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a model for multiple sclerosis.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量4071.9
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分子式C169H281N57O46S7
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纯度>98% (HPLC)
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溶解度water:2 mg/mL
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SMILES[H]NC(C(C)C)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC1CSSCC2NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCSC)NC(=O)CNC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC(=O)C3CSSCC(NC(=O)C(CC4=CNC=N4)NC(=O)C(CSSCC(NC(=O)C(CCC(N)=O)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(CC4=CNC=N4)NC(=O)C(CCCCN)NC1=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)N3)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(N)=O)NC(=O)C(NC2=O)C(C)O)C(=O)NC(C(C)O)C(=O)N1CCCC1C(=O)NC(CCCCN)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Han et al (2008) Structural basis of a potent peptide inhibitor designed for KV1.3 channel, a therapeutic target of autoimmune disease. J.Biol.Chem. 283 19058 PMID:
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